X Workshop on Apoptosis in Biology and Medicine
Ten year research in cell death and repair
University of Calabria 29-30 March, 2007
The X Workshop on Apoptosis in Biology and Medicine is organized in the frame of the PhD course on Pharmacology and Biochemistry of Cell Death run at the University of Calabria in consortium with the University Magna Graecia of Catanzaro and the University Tor Vergata of Rome. This will provide the students with the opportunity to meet with outstanding scentists of worldwide reputation in the field of pharmacology of cell death and repair and to discuss with them their research projects. The topics selected for this one and a half day meeting will range from basic mechanisms of neuronal cell death to the most recent experimental development of novel pharmacologic targets for therapeutical intervention. Starting in the year 1996 with the initial discussion on the biochemical and morphological features of apoptotic cell death and on the techniques developed for their identification, during the recent years the Workshop on Apoptosis in Biology and Medicine has been devoted to the discussion of hot topics concerned with the role of this type of cell demise in the development of human diseases like acute and chronic neurodegenerative disorders (stroke, Parkinson’s and Alzheimer diseases, neuroAIDS etc.) and cancer. Decipheration of the human genome has posed new opportunities for a better understanding of the pathophysiological mechanisms underlying human diseases though limitations of a pure genomic approach to the development of novel therapeutics have emerged. Identification, however, of key cellular effector molecules yielded the proteomic approach to the study of mechanisms of cell death and repair generating important results mainly in the field of clinical oncology. In the frame of the depicted “omic” scenario of biomedical research the workshop is the venue where the fundamental role of the multidisciplinary approach typically used by Pharmacology in the development of novel therapeutics will be presented.